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Nexium may require a shorter time and is slightly more effective in relieving heartburn and healing erosive esophagitis, though clinical significance has not been substantiated. Publicis’ Medicus Group handles professional marketing, and Manning, Selvage & Lee is the public relations agency. Still other payers, such as WellPoint Health Networks, Inc. , aren’t making drastic formulary changes but are promoting the adoption of Prilosec OTC to members, Our coupon program should help transition many members from Rx to OTC, says Rob Seidman, Pharm. , WellPoint’s chief pharmacy officer. Therefore, the FDA does not nexium otc believe that healthcare providers or patients should change either their prescribing practices or their use of these products at this time. " Prilosec OTC is the largest heartburn remedy on the market, generating $383. 9 million in revenue across food, drug and mass (minus Wal-Mart), according to data from Information Resources nexium otc inc. , representing a growth rate of 14 Nexium otc percent. She notes that AstraZeneca’s success with Nexium, which the company claims had worldwide sales of $1. 98 billion in 2002, will reduce the cost-savings potential of the Prilosec OTC switch. The ulcer drug category, primarily driven by proton pump inhibitors (PPIs) such as Prilosec, represents almost 9% of total drug costs for PBMs, according to AIS’s survey data. Among prescription drugs, standard doses of proton pump inhibitors Prevacid, Prilosec, Protonix, and Aciphex produce comparable rates of healing and remission in patients with erosive esophagitis, the panel states. To be sure, it’s not too far-fetched to theorize that AstraZeneca has no incentive to step up production of Prilosec OTC, a product the pharmaceutical company sans consumer division has licensed to Procter and Gamble for marketing over-the-counter. Both companies are making every effort to meet what has been described as a phenomenal demand that neither company foresaw. "America’s frequent heartburn is much more common than we could have ever predicted," commented Crystal nexium otc harrell, a P&G spokeswoman. Prilosec OTC by now has arrived on many drugstore shelves, and payers nexium otc hope to reap long-awaited savings from the event. "The goal is to maximize the best value in any of these therapeutic classes," commented Robert Seidman, chief pharmacy officer for WellPoint Health Networks. Nexium otc in response, P&G could claim that Prilosec shuts down acid flow, while Zantac 75 just slows acid production. Called DouglassBurke, nexium otc the new company is based in Horsham, Pa. Pfizer stated in a nexium otc news release that promotion will focus on Zantac 75 as a drug that relieves heart-burn fast, in contrast to Prilosec OTC, which can take one to four days for full effect. "There are some health plans that are adding Prilosec OTC to formulary and then requiring a treatment failure or contraindication of Prilosec OTC before a prescription PPI is covered. The OTC version of the drug will be pink, not the much-promoted purple used in the original Rx version. And while the nexium otc public positioning of each company is to be expected, that argument holds plenty of water. Panelists recommend that consumers consult a physician only if they experience severe, frequent, or prolonged symptoms for more than four weeks, thereby emphasizing the use of OTC drugs. Pepcid Complete, a combination of an H2 receptor antagonist and an antacid, was found to be better at symptom relief than the components used separately. He adds that this will be a gradual change, however, and predicts that it will take some time for Prilosec OTC to consume prescriptions. Lofgren says that perhaps greater cost-savings potential for the PPI category could nexium otc come from more manufacturers producing generic omeprazole, which has remained nearly as pricey as branded Prilosec because of production limitations.