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The problem has grown dramatically in recent years as direct-to-consumer advertising has increased, delivering ever-higher ad revenues to Lunesta prescription the nation’s media. And Plavix marketers Sanofi and Bristol-Myers Squibb amped up spending by 15% to lessen the impact from the brief generic clopidogrel launch. -Marc Iskowitz But spending in the first four months of this lunesta prescription year alone was already $48. 7 million; at that rate, it could top $146 million this year. While most of the eight FDA-approved sleep aids tend to lose their effectiveness after a week or so of use, Lunesta has been shown in Sepracor-funded clinical studies to remain effective for up to six months. As the April launch date approached, Sepracor ramped up its U. -based, primary care and specialty-oriented lunesta prescription sales force of 450. A lot of doctors have been lunesta prescription historically somewhat reticent to prescribe these drugs, so a patient-driven marketing approach makes sense, said analyst David Steinberg of Deutsche Bank North America. The firm also bought aggressively in journals, rising to 13th from 194th the prior year in spending on lunesta prescription professional advertising, according to PERQ/HCI data. Sepracor Chief Financial Officer David Southwell said he expects the market to eventually grow to $5. 5 billion because of lunesta prescription the new drugs and large number of insomniacs who go untreated. LED BY THE sleep aid category, drug firms upped consumer advertising by a healthy margin in 2006, data from advertising intelligence firms show. Market for sleep aids at Lunesta prescription $3. 5 billion a year and growing. Figures from TNS Media Intelligence, another research company, reflect a rise of 10% among the top 10, from $1. 09 billion to $1. 2 billion during the year’s first nine months vs. Are teaming up to develop indiplon, a GABA-receptor drug that hasn’t yet been given a brand name, and Japan-based Takeda Pharmaceuticals is developing Rozerem, Lunesta prescription a drug that interacts with the natural hormone melatonin. Sepracor last month announced it would begin distribution of its recently approved treatment for insomnia, Lunesta. We do that on our own. The Benicar franchise, from Sankyo and Forest Pharmaceuticals, also posted remarkable growth figures. But last year, with a sharpened, more goal-oriented message, stronger visuals and increased investment in advertising, Sankyo and Forest made some marketing adjustments and managed to grow Lunesta prescription both monotherapy and combination product. Sanofi-Aventis boosted DTC promotion for its Ambien franchise lunesta prescription from $2 million to $160 million to support the launch of a new extended-release version, Ambien CR. Through October, the spending level for all prescription drugs was on pace for an 8% hike over the Lunesta prescription first 10 months of 2006, to $3. 82 billion from lunesta prescription $3. 5 billion, according to data from Nielsen Monitor-Plus. But the Lunesta team orchestrated a highly disciplined launch campaign, helping carry its drug and the entire sleep aids category to new heights. Driving the increase was Lunesta, which looks set to unseat Nexium as the top DTC spender for the year. An estimated 126 million adult Americans experience at least one insomnia symptom a few nights a week, according to the National Sleep Foundation, a group which receives some of its funding from drug companies.